Homology Modeling Study of Bovine μ-Calpain Inhibitor-Binding Domains
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چکیده
منابع مشابه
Homology Modeling Study of Bovine μ-Calpain Inhibitor-Binding Domains
The activated mammalian CAPN-structures, the CAPN/CAST complex in particular, have become an invaluable target model using the structure-based virtual screening of drug candidates from the discovery phase to development for over-activated CAPN linked to several diseases, such as post-ischemic injury and cataract formation. The effect of Ca²⁺-binding to the enzyme is thought to include activatio...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2014
ISSN: 1422-0067
DOI: 10.3390/ijms15057897